Protein Info for BBR_RS20105 in Bifidobacterium breve UCC2003

Annotation: YhgE/Pip domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 779 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 532 to 551 (20 residues), see Phobius details amino acids 623 to 646 (24 residues), see Phobius details amino acids 653 to 673 (21 residues), see Phobius details amino acids 683 to 702 (20 residues), see Phobius details amino acids 737 to 758 (22 residues), see Phobius details TIGR03061: YhgE/Pip N-terminal domain" amino acids 12 to 172 (161 residues), 128.1 bits, see alignment E=2.5e-41 PF12698: ABC2_membrane_3" amino acids 29 to 224 (196 residues), 38.7 bits, see alignment E=3.5e-14

Best Hits

KEGG orthology group: None (inferred from 82% identity to blo:BL0137)

Predicted SEED Role

"FIG00425928: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (779 amino acids)

>BBR_RS20105 YhgE/Pip domain-containing protein (Bifidobacterium breve UCC2003)
MKLIWKIFARDVRQSTRNVIAVIVAMGLVIVPALYAWYNIAASWDPYGNTKALKVAVANV
DKGYKSDLMPITINVGETVTNTLRANHDLDWQFVDKDEAIDGVNSGAYYAALIIPKSFSA
DMMTVFSPTIKHAKIEYYLNEKINPIAPHITDQGASTVATTIDQTFVKTLASVALDLVSN
VSNYAQSPQMAQYVNNATSHISTMSSRLTVAASQMDSYANLLGAANGIIDSTDKLLGSTG
SAANTAKKALKQTRDGVNSLDSALSGAASGVETALQQAGASYDTVSKQLDTAFASIGSQS
DQISGTLTDMQTKVNDQSASFGAYASALRELAGKSSSLPAGGDTIAKRLNAAADQATQTQ
QDLKNVADDLGRAAQSLVDGTADTDQTLKDIKAQIAAAKQSVTQAANDYQSTLKPQLNNL
TASMGDVADQASSVIDGLSSTVNSVSNLSGGISASLRDIQTTLTDAAGNLNHSASKLDDL
SAQLSGIASGSSTDLDSITTADPDAIASLLSAPVAVDRIPLYPVANYGSAMAPFYTILSI
WVGAIILVAMMKVSVSDHEKAKILGFGNDLPLGSEVGLREAMIAGRVAGPAAALDVLTKP
RADSPGNARQFGLHLYQEYFGRYMLFGFLALLQGTLVCLGDMFYLGVQCEHPVQFLMVGW
LSALVFSNIVYTLTLSFGDIGKAIAVVLLVMQVAGSGGTFPIETLPSFFQAASKWLLFPY
AVDAMHSAMAGSYGMEYWVSMGKLALFLVPSLLLGLLLRRPVIRFNDWIIRNLESTKVM