Protein Info for BBR_RS20080 in Bifidobacterium breve UCC2003

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF01547: SBP_bac_1" amino acids 54 to 356 (303 residues), 59.3 bits, see alignment E=6.8e-20 PF13416: SBP_bac_8" amino acids 60 to 380 (321 residues), 156 bits, see alignment E=1.8e-49

Best Hits

KEGG orthology group: None (inferred from 98% identity to blm:BLLJ_1859)

Predicted SEED Role

"Multiple sugar ABC transporter, substrate-binding protein" in subsystem Fructooligosaccharides(FOS) and Raffinose Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (448 amino acids)

>BBR_RS20080 ABC transporter substrate-binding protein (Bifidobacterium breve UCC2003)
MKEKGSMMNRTVKSAVAVAAIAAMSLGTLAACGSSTSGDDSKGKVYYLNFKPEAADQWTA
LAKEYTKEKGVEVKVQTAASGTYEQTLKSEIAKTEAPTLFQVNGPVGYQNWKKYTADMSN
TDVYKELTNQDVALKDGDKVVGVPYVMETYGLIYNKDILNKYFALDGAKATSMDEIDNFD
TLKAVADDMQSRKDELGIKGAFTSAGFDSSSDWRFKTHLANLPLYYEFKDDNVTEQPAKI
KGTYLPNYKKIFDLYITDSTTEPTQLSAKTGDDANSEFALGEAAFYQNGTWAWTDLQKAG
MKAESVGMMPIYIGVKGEEKQGLATGSENYWCINDKASDADKKATEDFLSWVITSDTGKK
ALSQDMGFTTPFKTFDDVKSDNPLTEAAVEDQKSGKTQVSWNFTMMPSEEWKNKIGQALL
EYAQGTGNWDAVKTAFVDGWASEYEASH