Protein Info for BBR_RS19895 in Bifidobacterium breve UCC2003

Annotation: aminopeptidase C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 PF03051: Peptidase_C1_2" amino acids 10 to 241 (232 residues), 253.5 bits, see alignment E=3.7e-79 amino acids 295 to 495 (201 residues), 219.3 bits, see alignment E=9.2e-69

Best Hits

KEGG orthology group: K01372, bleomycin hydrolase [EC: 3.4.22.40] (inferred from 96% identity to bll:BLJ_1941)

Predicted SEED Role

"Aminopeptidase C (EC 3.4.22.40)" in subsystem Protein degradation (EC 3.4.22.40)

Isozymes

Compare fitness of predicted isozymes for: 3.4.22.40

Use Curated BLAST to search for 3.4.22.40

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (500 amino acids)

>BBR_RS19895 aminopeptidase C (Bifidobacterium breve UCC2003)
MTTDASARAIKPELLRTYTEDFNKDRANLIAADAAVSAGVLKAATDYRGVRALPRDFSIE
LKQGSITNQERSGRCWMFASLNTLRYELMHRWNLEDFEFSETYLFFWDAMEKSNTYLENV
LRTLDEPTDSRLFEAINWGPSDDGGWWQMFAALVNKYGLVPKSAYPESENSRNSDDFKQY
LNSKLREFAAELRRRSAAGAGEDELRTLKDEYMGTVYRICAVSLGEPPEKFDFFARTKDD
AEDDKKCDGKACKRKADADGKDESCKCEDKSDAKACKCDKNKDKTGKDERPQIREIGITP
LEFYKKYVPVDVNDFATLANAPLKSRPFNRRYRIRFSANVAEAGDMEFVNVPLDVFKKAA
LDQLTAGHPIWFACDCTQFALRKDGFFDQSVVRVDQLFGTEFTGDKAHGLEYGDSPSNHA
MTFTGVNLGEDGKPNRWKVENSWGKDAGKDGYYVMSDAWFDRYVTELIIRKEYLDDATRA
LLTTEPVELDPWLPLTRRCR