Protein Info for BBR_RS19695 in Bifidobacterium breve UCC2003

Annotation: tRNA glutamyl-Q(34) synthetase GluQRS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 transmembrane" amino acids 12 to 28 (17 residues), see Phobius details PF00749: tRNA-synt_1c" amino acids 3 to 154 (152 residues), 94 bits, see alignment E=4.4e-31 amino acids 183 to 314 (132 residues), 38.3 bits, see alignment E=3.8e-14

Best Hits

Predicted SEED Role

"glutamyl-Q-tRNA synthetase" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (365 amino acids)

>BBR_RS19695 tRNA glutamyl-Q(34) synthetase GluQRS (Bifidobacterium breve UCC2003)
MTGRFAPTPSGRMHIGNVYAMLAAWLSARSRGDRMLMRIEDVDKPRVIAGADRLMLDDLR
WLGLDWDGEPIFQSQRTERYEYALECLRSRGVLYPCFCSRADIRAASAPNEGDGFMVYPG
TCRHLLRNHSGEVHSRLARGDQHSVRIAMPEPRAMSDGPFANLYTSSEASTPVRGDGIAD
CITSFDDCVYGPQHYDLPHEVGDSVIRRADGLFGYQLVVVVDDLDMGVDDIVRGRDLLRS
TALQMWIRQCLLAGGFRPECASDARVSAEHPKYVHLPLIDNAAGRRLAKRERSLDMGALR
ARGVTPEQIIGYCAWLLRLQSIPIPCKPADLLADFSWEPLRANHPDRALKPDDPTTPQWL
AEALG