Protein Info for BBR_RS19530 in Bifidobacterium breve UCC2003

Annotation: septum formation protein Maf

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 483 PF02545: Maf" amino acids 4 to 91 (88 residues), 27.5 bits, see alignment E=2.4e-10 amino acids 158 to 280 (123 residues), 112.6 bits, see alignment E=1.9e-36 TIGR00172: septum formation protein Maf" amino acids 151 to 275 (125 residues), 119.7 bits, see alignment E=5.3e-39 PF00293: NUDIX" amino acids 356 to 458 (103 residues), 59.5 bits, see alignment E=3.7e-20

Best Hits

Swiss-Prot: 96% identical to NTPNH_BIFLO: Nucleoside triphosphate pyrophosphatase/Nudix hydrolase fusion protein (BL1276) from Bifidobacterium longum (strain NCC 2705)

KEGG orthology group: K06287, septum formation protein (inferred from 96% identity to bll:BLJ_1840)

Predicted SEED Role

"Septum formation protein Maf" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (483 amino acids)

>BBR_RS19530 septum formation protein Maf (Bifidobacterium breve UCC2003)
MSIPLILASKSKPRRDVLYSAGICPTIRVSHVDEPAALEAAAREEGVTVDDLSIKQRVMI
LATAKAEAVHRAYRDVADTAAAATGDRVIAYPLKAKEIKDSEREAAVEDLCKAAAGKPID
YSKAEIATTRDFSGIDMPTVTEPIATAIAGQSGLTEATVGPLILGCDSMFLLDGECYGKP
HSEAVARERLKRMSGATGELWTGHCLIDFATGRTVRGASHAKVHFGEFTDDDIERYIATG
EPLEVAGSFTLEGFGGAFIDSIEGDPHGIIGLSLPLARHLAGELGVKWTDLWNVDRGELA
PESKASGNQHAGILPPVENVHQPGDGWVDCACGRKHWGTNGASGILLARRDAASGKVTHV
VMQHRAAWSAEGGTWGIPGGATADGESPIEGALRESYEEANITPEDIEVVGSYREDHGPW
AYTTVFAFEKSGYTVEPKANDDESMEVCWVPIADVPNRKLLTAMKTDWPRFAARLDELAA
AQG