Protein Info for BBR_RS19470 in Bifidobacterium breve UCC2003

Annotation: succinyl-diaminopimelate desuccinylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01900: succinyl-diaminopimelate desuccinylase
  • amino acids 12 to 400 (389 residues), 523.4 bits, E=1.2e-161
• PF04389: Peptidase_M28
  • amino acids 58 to 156 (99 residues), 21.3 bits, E=2.9e-08
• PF01546: Peptidase_M20
  • amino acids 71 to 399 (329 residues), 79.1 bits, E=7e-26
• PF07687: M20_dimer
  • amino acids 195 to 288 (94 residues), 64.1 bits, E=1.6e-21

Best Hits

KEGG orthology group: K01439, succinyl-diaminopimelate desuccinylase [EC: 3.5.1.18] (inferred from 93% identity to bln:Blon_2303)

Predicted SEED Role

"N-succinyl-L,L-diaminopimelate desuccinylase (EC 3.5.1.18)" in subsystem Arginine Biosynthesis extended or Lysine Biosynthesis DAP Pathway (EC 3.5.1.18)

MetaCyc Pathways

• aspartate superpathway (23/25 steps found)
• superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (16/18 steps found)
• L-lysine biosynthesis I (9/9 steps found)

KEGG Metabolic Maps

• Lysine biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.18

Protein Sequence (401 amino acids)

>BBR_RS19470 succinyl-diaminopimelate desuccinylase (Bifidobacterium breve UCC2003)
MTLELNRNDSTAEQLNSLLIQIMENFSVSDHEGPLADEVEAFLNEQKHLTVRRHGDTVVA
STDFGKSNRVILAGHLDTVPVIDNFPPKWLEPGDPLIREEISQSHPTDRVLWGRGATDMK
ASDAVMLYLAATLDGLTSGTTPKVDLTYVFYDHEEVAAEKNGLRKVVETHPDWIAGDFAI
IGEPTNSGIEGGCNGTIRFDVVTHGVAAHSARAWMGENAIHKAADILNRLNAYETATVNV
DGLDYREGLNATLISGGKGTNVIPDECRVHVNYRFAPDKNLAEAKALMMGADAGAELGNG
EHVATGGVFEGYGIEMKDESPSARPGLSAPLAQELVRLVKERTGRDPLAKLGWTDVARFS
QLGIPAVNLGAGDPLLAHKHDEQVPESDLTAMAAILEDWLV