Protein Info for BBR_RS19050 in Bifidobacterium breve UCC2003

Annotation: succinyldiaminopimelate transaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03539: succinyldiaminopimelate transaminase
  • amino acids 10 to 393 (384 residues), 369.9 bits, E=6.7e-115
• PF00155: Aminotran_1_2
  • amino acids 29 to 393 (365 residues), 139.9 bits, E=6.3e-45

Best Hits

KEGG orthology group: None (inferred from 82% identity to bln:Blon_2251)

Predicted SEED Role

"N-succinyl-L,L-diaminopimelate aminotransferase alternative (EC 2.6.1.17)" in subsystem Lysine Biosynthesis DAP Pathway (EC 2.6.1.17)

MetaCyc Pathways

• aspartate superpathway (23/25 steps found)
• superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (16/18 steps found)
• L-lysine biosynthesis I (9/9 steps found)

KEGG Metabolic Maps

• Lysine biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.17

Use Curated BLAST to search for 2.6.1.17

Protein Sequence (395 amino acids)

>BBR_RS19050 succinyldiaminopimelate transaminase (Bifidobacterium breve UCC2003)
MGFHAYSSPYDWSRIAGFKAAAKAVPGGMIDLSVGSPVDSVPDAVQQALASTADASNAHG
YPVTAGTVDLKSAIDSWFRNMRGVDLKAVNAAVIPTVGSKEAVALMASLLHLGEGDVVVQ
PKVSYPTYEIGTQLAGATVAKVDDVTDVDSWVNIPNVKAIWINSPCNPTGEVISADWLAD
IVAAARRIGAVVLSDECYALMDWRSARNTTSRPAAASNEPASDAAFSLFATPCALNQQVC
EGSADGILVLYSLSKQSNMAGYRTALIAGDYRLVAEMGEYRKQIGQIIPGPVQAAMAAGL
NDAGSVYAQWNRYRGRLVALVDALNAYGYQAQMPSGALYVWVKAKSGDCWSDMAELAQLG
IIPSPGEFYGAPEYLRFSATATDDAIDAACQRLMA