Protein Info for BBR_RS19030 in Bifidobacterium breve UCC2003

Annotation: LacI family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 PF00356: LacI" amino acids 5 to 50 (46 residues), 51.5 bits, see alignment 6.9e-18 PF13377: Peripla_BP_3" amino acids 213 to 373 (161 residues), 98.1 bits, see alignment E=6.3e-32

Best Hits

Predicted SEED Role

"Maltose operon transcriptional repressor MalR, LacI family" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (375 amino acids)

>BBR_RS19030 LacI family transcriptional regulator (Bifidobacterium breve UCC2003)
MRRATVYDVAKKAGVSTATVSFTFRRPDKVKPSTRAKVLRAAKDLDYVPSANARGLARGN
TGVLGLYSFDMLIERPLGDEDDFDSCSGGNDVVSENGKPIFSNRAGESFDCPSVLSYPLY
VDEVQRGFELECRRRNRAVLLGTAIRHDDGAGITDVAGRVDGLAVFPNEFTSTMPLEALC
RSIPIVRLSEGDGDEPAAYISCDNETGMNQLIDHLVDVHGVHDMEFVGSLDNYDSRHRFA
AMRAKLKMKGLRVPDLPLDDSVSGTHEWFVDLCEVIDAGRLPQALLCATDQTAFEVMSVL
RDAGVRVPQDVILTGFDGVLAGQVLTPTLTTVRQPLELLGQLAARLLDEQAGEPWGKPER
FRLPVKLIVRGSCGC