Protein Info for BBR_RS18930 in Bifidobacterium breve UCC2003

Annotation: 50S ribosomal protein L4

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 PF00573: Ribosomal_L4" amino acids 34 to 208 (175 residues), 215.5 bits, see alignment E=2.6e-68 TIGR03953: 50S ribosomal protein uL4" amino acids 34 to 208 (175 residues), 214.4 bits, see alignment E=4.2e-68

Best Hits

Swiss-Prot: 95% identical to RL4_BIFLO: 50S ribosomal protein L4 (rplD) from Bifidobacterium longum (strain NCC 2705)

KEGG orthology group: K02926, large subunit ribosomal protein L4 (inferred from 95% identity to blj:BLD_1708)

Predicted SEED Role

"LSU ribosomal protein L4p (L1e)" in subsystem Ribosome LSU bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (218 amino acids)

>BBR_RS18930 50S ribosomal protein L4 (Bifidobacterium breve UCC2003)
MANVTLNVTDAKGQAAGTVEAPVELFGVSAEDVKAHIPLIHQVVTAQLAAARQGTHATKT
RGMVSGGGKKPWKQKGTGRARQGSIRAPQWYHGGVVFGPQPRDYSQRTPKKMKAAALRYA
LSDRANAGRIAVVDFGITEPSTKAAVAALSPITEDKFTTVVFTRDNINEWLSVRNIPTVH
PIFVDQLNTYDVITAQYVVFTKEAFEAFVAAKTEPKEA