Protein Info for BBR_RS18695 in Bifidobacterium breve UCC2003

Annotation: PRD domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 PF03123: CAT_RBD" amino acids 1 to 49 (49 residues), 65.5 bits, see alignment 3.3e-22 PF00874: PRD" amino acids 74 to 163 (90 residues), 36.5 bits, see alignment E=5e-13 amino acids 181 to 273 (93 residues), 56.7 bits, see alignment E=2.4e-19

Best Hits

KEGG orthology group: K03488, beta-glucoside operon transcriptional antiterminator (inferred from 65% identity to bbi:BBIF_1454)

Predicted SEED Role

"Beta-glucoside bgl operon antiterminator, BglG family" in subsystem Beta-Glucoside Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (297 amino acids)

>BBR_RS18695 PRD domain-containing protein (Bifidobacterium breve UCC2003)
MEILRVFNNNVVLAKDRGREVILTGRGLGFKAKPGMTVDDAKVARVFVPAQGRDPDHMAQ
LLGDIPPEIIRLISETMDEIGLSSEAAQSSTLVMALADHVCGALRRAKNGIPPVPYPLNS
EIRSLYKREYQQGCALLAALNRRLDDALDPSESVAFALHFVNAGFSTGDLSPTYMMTGVI
QQLLAVIESTYNIKLDEHSVNVGRFITHLRYLFVRIHQHEQLSREPEAIVSSIMSSYAKA
SKCARLIASLIELRLDTTLTEDEVAYLTLHVARVTDQTNQNRSSDIPDHPQLAHMGQ