Protein Info for BBR_RS18675 in Bifidobacterium breve UCC2003

Annotation: Solute-binding protein of ABC transporter system for sugars

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF01547: SBP_bac_1" amino acids 60 to 338 (279 residues), 94.7 bits, see alignment E=5.3e-31

Best Hits

KEGG orthology group: K02027, multiple sugar transport system substrate-binding protein (inferred from 98% identity to blj:BLD_1762)

Predicted SEED Role

"Predicted galacto-N-biose-/lacto-N-biose I ABC transporter, periplasmic substrate-binding protein" in subsystem Lacto-N-Biose I and Galacto-N-Biose Metabolic Pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (438 amino acids)

>BBR_RS18675 Solute-binding protein of ABC transporter system for sugars (Bifidobacterium breve UCC2003)
MVSHNKRIVAALAAVAAMGIGLAGCGGSDTAGDTKSGSDGGVVNITYMHRLPDSEGMTLV
NDIVAKWNKEHPNIQVKATKFDGNASEMIKKLETDVKAGNAPDLAQVGYAEVPEVFTKGL
LQDVTDEAAKYKDDFASGPFALMQVGGKTYGLPQDTGPLTYFYNAAEFEKLGITVPKTAD
ELIETAKKTAAQGKYIMTFQPDEAMMMMSGQAGASGPWYKVDGNSWVVNTQTKGSKAVAD
VYQQLIDNKAALTNPRWDASFDNSIQSGQLIGTVAAAWEAPLFIDSAGGTGAGEWKVTQL
GDWFGNGTKTGADGGSGVAVLKGSKHPAEAMEFLDWFNTQVDDLVSQGLVVAATTAEAKT
PQKWSDYFSGQDVMAEFKTANGNMGDFTYMPGFSAVGAAVKQTAAKAADGSAKVSDVFDT
AQKTSVDTLKNLGLSVKE