Protein Info for BBR_RS18150 in Bifidobacterium breve UCC2003

Annotation: energy-dependent translational throttle protein EttA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 559 TIGR03719: ATP-binding cassette protein, ChvD family" amino acids 3 to 555 (553 residues), 877.5 bits, see alignment E=3.7e-268 PF00005: ABC_tran" amino acids 21 to 190 (170 residues), 83.4 bits, see alignment E=7.3e-27 amino acids 340 to 473 (134 residues), 76.4 bits, see alignment E=1.1e-24 PF12848: ABC_tran_Xtn" amino acids 229 to 305 (77 residues), 55.4 bits, see alignment E=1.7e-18

Best Hits

Swiss-Prot: 72% identical to ETTA_MYCTO: Energy-dependent translational throttle protein EttA (ettA) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

KEGG orthology group: None (inferred from 100% identity to bll:BLJ_1625)

Predicted SEED Role

"ABC transporter ATP-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (559 amino acids)

>BBR_RS18150 energy-dependent translational throttle protein EttA (Bifidobacterium breve UCC2003)
MAEFVFQMIKARKSYGDRVILDDVTLSFLPGAKIGVVGPNGMGKSTLLKIMAGLETVSNG
EATLTPGFTVGILQQEPPLDDTKTVGENIKMAFGPIAEKVARFNAIGEEMANPDADFDAL
MEEMGKLQTEIDAADGWDLDSQLEQAMDALQCPDPDTPVNVCSGGERRRVALCKLLLEAP
DLLLLDEPTNHLDAESILWLEQFLHQYKGAVIAVTHDRYFMDNVAEWICEVDRGHLYPYK
GNYSTYLETKAKRLEIQGAKDAKLAKRLKNELDWVRSSPKARQAKNKARLERYDQMENEA
RNNKKLDFSEIQIPAGPRLGSTVLEAKHIHKAFGERVLIDDLSFTLPRNGIVGVIGPNGV
GKSTLFKTIVGLEPLTSGELKIGDTVKISYVDQNREGLDPNKNLWEAVSGGLDFIEVAGV
EVPTRAYVASFGFKGADQQKLTGVLSGGERNRLNLALTLKQGGNLLLLDEPTNDLDVETL
ESLENALLEFPGCAVVISHDRWFLDRVATHILAWEGDDDNPAKWYWFEGNFQAYQENKVA
RLGEDAARPHRLHKKLVRG