Protein Info for BBR_RS18050 in Bifidobacterium breve UCC2003

Annotation: threonylcarbamoyl-AMP synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 228 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family" amino acids 14 to 218 (205 residues), 147.9 bits, see alignment E=1.1e-47 PF01300: Sua5_yciO_yrdC" amino acids 26 to 208 (183 residues), 156.8 bits, see alignment E=2.1e-50

Best Hits

KEGG orthology group: None (inferred from 87% identity to bll:BLJ_1579)

Predicted SEED Role

"TsaC protein (YrdC domain) required for threonylcarbamoyladenosine t(6)A37 modification in tRNA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (228 amino acids)

>BBR_RS18050 threonylcarbamoyl-AMP synthase (Bifidobacterium breve UCC2003)
MNQVNGDGMSATRKVTDESLAQAARIIHDGGLIVIPTDTVYGVACDPRNAAAIARIYELK
RRPRYKALQVLLDSTDQLDELGLELPSPLNRLSAAFLPGAFSPIAVARPDCTLETLADTA
EGRPGTQGIRIPNSALCLEILRATGPLAASSANRSGDESAQTVDEAVEAFGNQIDLYLDG
GPTQGHISSTVVKADPYARDGIEILREGVIPQSMIRKALHLNGGGLGA