Protein Info for BBR_RS18030 in Bifidobacterium breve UCC2003

Annotation: helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 472 transmembrane" amino acids 63 to 82 (20 residues), see Phobius details PF13604: AAA_30" amino acids 3 to 153 (151 residues), 58.8 bits, see alignment E=1.9e-19 PF13245: AAA_19" amino acids 3 to 143 (141 residues), 49.7 bits, see alignment E=1.3e-16 PF05970: PIF1" amino acids 9 to 152 (144 residues), 122.9 bits, see alignment E=4.5e-39 PF13401: AAA_22" amino acids 15 to 135 (121 residues), 32.7 bits, see alignment E=2.5e-11 PF21530: Pif1_2B_dom" amino acids 276 to 320 (45 residues), 28.7 bits, see alignment 2.6e-10

Best Hits

KEGG orthology group: None (inferred from 95% identity to blm:BLLJ_1537)

Predicted SEED Role

"putative helicase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (472 amino acids)

>BBR_RS18030 helicase (Bifidobacterium breve UCC2003)
MRQTEALAILNAGANVFLTGAPGAGKTYVLNEFIRQARADGVSVAVTASTGIASTHINGQ
TIHSWSGVGVATSLTSSLLKLIKSRRKRKIQATDILVIDEVSMLHAWLFDMVDQVCREVR
RDPRPFGGIQVVLSGDLFQLPPVSVSGRNRDLIEPTPEFIASRERYARAGLNPESFITES
LVWQELNPVICYLTEQHRQDTGELLTVLTDIREGDVTQSDRDALVTRLGKLPEPGQVAVH
LFPVNRQADNLNDMRLNQIMLEPHEFHAETAGPANLVDRLKKNMLAPERLVLKEGAAVMA
LRNDPDRQYVNGSLGTVRGFAQENKGGWPIVEFENGNIVTMKQAKWEMMDGETVLASVAQ
VPLRCAWGITIHKSQGMTLDRAVMDLKRTFAPGMGYVALSRVESLGGLYLAGVNERMFLV
SPDAVVLDGDLREASASASDQLADEGAGAFKPTEPDEFAADPNDEFAQDALF