Protein Info for BBR_RS17910 in Bifidobacterium breve UCC2003

Annotation: anaerobic ribonucleoside-triphosphate reductase activating protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 242 TIGR02491: anaerobic ribonucleoside-triphosphate reductase activating protein" amino acids 51 to 203 (153 residues), 165.8 bits, see alignment E=3.3e-53 PF13353: Fer4_12" amino acids 61 to 200 (140 residues), 177.8 bits, see alignment E=7e-57

Best Hits

KEGG orthology group: K04068, anaerobic ribonucleoside-triphosphate reductase activating protein [EC: 1.97.1.4] (inferred from 100% identity to bln:Blon_0613)

Predicted SEED Role

"Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)" in subsystem Ribonucleotide reduction (EC 1.97.1.4)

Isozymes

Compare fitness of predicted isozymes for: 1.97.1.4

Use Curated BLAST to search for 1.97.1.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (242 amino acids)

>BBR_RS17910 anaerobic ribonucleoside-triphosphate reductase activating protein (Bifidobacterium breve UCC2003)
MPELHTTKPEPKRHDFAAGETGRGPSVPSNGLANDPKAGQWDGRRMSKRMIADYKTFIVT
DGEGVRNSLYVSGCPFHCVDCFNASIWDFQAGHEYTQKLEDKIIEDLKAPWVQGITFLGG
EPFLNTPVLVPLAQRIRQEFGHTKDIWSWTGYTWEELMRPGETPDKLELLHLIDILVDGR
YLRDQKDSLLQFRGSRNQRILDVPKSLEAGEPVIWAKLHDQERDIPEIYLKDREAGEGQQ
AS