Protein Info for BBR_RS17760 in Bifidobacterium breve UCC2003

Annotation: D-ribose ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF00532: Peripla_BP_1" amino acids 38 to 294 (257 residues), 86.3 bits, see alignment E=4e-28 PF13407: Peripla_BP_4" amino acids 40 to 292 (253 residues), 219.3 bits, see alignment E=1.1e-68 PF13377: Peripla_BP_3" amino acids 166 to 298 (133 residues), 46.3 bits, see alignment E=8e-16

Best Hits

Swiss-Prot: 45% identical to RBSB_SALTY: Ribose import binding protein RbsB (rbsB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K10439, ribose transport system substrate-binding protein (inferred from 98% identity to bll:BLJ_1519)

MetaCyc: 45% identical to ribose ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-28-RXN

Predicted SEED Role

"Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (314 amino acids)

>BBR_RS17760 D-ribose ABC transporter substrate-binding protein (Bifidobacterium breve UCC2003)
MLNSTMKKTFRAALAIVCAGTLMAGTAACGSTSSSGGDKVALLVSTLNNPFFVDLRDGAQ
AAAKDLGVDLMVSDAQNDSSTQQNQAQNAQSQGAKAVIINPVDSDAASPAVAPLLSSSLP
VISVDRSVTGEDVTSHIASDNVAGGAQAADELAKAVGEKGKVIILQGTPGAASTRDRGDG
FKKEIKKYSGIEVVAEQTANFDRAEALDVTTNLMQSNPDVVGIYAENDEMALGAIQSLGS
KAGADVKIFGFDGTEDGLKAVSNGTMVGTIAQQPKELGKKAVEAAVKAIKGESVEKTESI
EVKTVTKGNVADFQ