Protein Info for BBR_RS17570 in Bifidobacterium breve UCC2003

Annotation: ribulose-phosphate 3-epimerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00834: Ribul_P_3_epim
  • amino acids 7 to 200 (194 residues), 175 bits, E=6.3e-56

Best Hits

Swiss-Prot: 48% identical to ALSE_ECOLI: D-allulose-6-phosphate 3-epimerase (alsE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 66% identity to sak:SAK_1758)

MetaCyc: 48% identical to D-allulose-6-phosphate 3-epimerase (Escherichia coli K-12 substr. MG1655)
5.1.3.-

Predicted SEED Role

"Ribulose-phosphate 3-epimerase (EC 5.1.3.1)" in subsystem Calvin-Benson cycle or Conserved gene cluster associated with Met-tRNA formyltransferase or Pentose phosphate pathway or Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization (EC 5.1.3.1)

MetaCyc Pathways

• Bifidobacterium shunt (15/15 steps found)
• heterolactic fermentation (16/18 steps found)
• pentose phosphate pathway (8/8 steps found)
• superpathway of glucose and xylose degradation (14/17 steps found)
• pentose phosphate pathway (non-oxidative branch) I (5/5 steps found)
• pentose phosphate pathway (partial) (3/3 steps found)
• Rubisco shunt (8/10 steps found)
• pentose phosphate pathway (non-oxidative branch) II (5/6 steps found)
• formaldehyde assimilation III (dihydroxyacetone cycle) (9/12 steps found)
• formaldehyde assimilation II (assimilatory RuMP Cycle) (6/9 steps found)
• D-allose degradation (1/3 steps found)
• Calvin-Benson-Bassham cycle (8/13 steps found)
• ethene biosynthesis V (engineered) (16/25 steps found)
• oxygenic photosynthesis (9/17 steps found)
• 1-butanol autotrophic biosynthesis (engineered) (13/27 steps found)
• photosynthetic 3-hydroxybutanoate biosynthesis (engineered) (12/26 steps found)

KEGG Metabolic Maps

• Carbon fixation in photosynthetic organisms
• Pentose and glucuronate interconversions
• Pentose phosphate pathway

Isozymes

Compare fitness of predicted isozymes for: 5.1.3.1

Use Curated BLAST to search for 5.1.3.1

Protein Sequence (238 amino acids)

>BBR_RS17570 ribulose-phosphate 3-epimerase (Bifidobacterium breve UCC2003)
MTRKIQLSPSLMTMDLDQFKEQITFLNDKVNSFHIDVMDGHFVPNITLSPWFVEQVRKIS
DVPMSAHMMVMDAPFWVERLIEVKCDYICFPSEVANGVAFSIIDKIHAAGLKAGAVLNPE
TSIDVIKPYIDLLDKITIMTIDPGFAGQRFLESTLDKIVELRALREEMGYNYEIEMDGST
NKAHWKMISDANPDVYVIGRSGLFGLTDNIESSWNQMVSEYEECTGFQFDNGLYTTAK