Protein Info for BBR_RS17565 in Bifidobacterium breve UCC2003

Annotation: proteasome accessory factor PafA2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 554 TIGR03688: proteasome accessory factor PafA2" amino acids 4 to 537 (534 residues), 673.7 bits, see alignment E=7.8e-207 PF03136: Pup_ligase" amino acids 5 to 485 (481 residues), 498.7 bits, see alignment E=8.5e-154

Best Hits

KEGG orthology group: None (inferred from 88% identity to blb:BBMN68_23)

Predicted SEED Role

"Pup ligase PafA' paralog, possible component of postulated heterodimer PafA-PafA'" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Proteasome archaeal

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (554 amino acids)

>BBR_RS17565 proteasome accessory factor PafA2 (Bifidobacterium breve UCC2003)
MSVKRVMGTETEYAVSLSGAGRYNPVQLSFDVVNGAAGSHSKNIRWDYRQEDPVNDARGT
RLERAAARPDMLTDAPQLNITNVIAPNGGRVYVDHAHPEYSAPETTDPFEAVLYDHAGDL
IMQAATERASSQTGTPIELHRNNVDGKGSCWGTHENYMMARAVPFDQVTRLMTLHFVTRQ
IYAGSGRVGIGERSEMPGYQLSQRADYIHAKVGLQTTFERPIINTRDESHATDEYRRLHV
IVGDANRMDVPQVLKLGTTSMLLWLLEHADEAGFDLNAFLDELELADPVEAVHIVSHDLT
LDAALPLANGGETTAWLIQLKLRQAVYQVAALIDGTDTSGEPAWPDKSTTSVMAMWGQAL
ADCVAIRHADADQRLTMTGEASRVEWLLKWQLLEKLRRKITGAATPDAANGWDDSRLKVI
DLKWAALDSRDSVFAKLEPRTERVNAAADLARATTEPPENTRAWLRAKLVERFGVEVAAV
SWSRLTARDPNAVDAGEATEFYGNAGHMAAPDHHLFSLDISDPLAYGKARCEAKLNAAEH
AIDLLKALAINGER