Protein Info for BBR_RS17110 in Bifidobacterium breve UCC2003

Annotation: oleate hydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 625 PF06100: MCRA" amino acids 23 to 555 (533 residues), 713.4 bits, see alignment E=1.6e-218 PF13450: NAD_binding_8" amino acids 27 to 79 (53 residues), 25.9 bits, see alignment 9.8e-10

Best Hits

KEGG orthology group: K10254, myosin-crossreactive antigen (inferred from 98% identity to blb:BBMN68_175)

Predicted SEED Role

"Oleate hydratase (EC 4.2.1.53)" (EC 4.2.1.53)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.1.53

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (625 amino acids)

>BBR_RS17110 oleate hydratase (Bifidobacterium breve UCC2003)
MYYSSGNYEAFARPKKPAGVDSKHAYIIGTGLAALSSACYLVRDGQMPGDHIHILEKDPV
PGGACDGLDIPGLGYVMRGGREMDNHFEVMWDLFRSIPSIETEGVSVLDEYYWLNKEDPN
YSLCRATKDLGKDAGLKGKFGLSDKASMEIMKLFFTPDEDLYDKPITDFFDDEVLNSNFW
LYWRTMFAFENWHSALEMKLYIKRYIHHIGGLPDFSALRFTRYNQYESMILPMVKYLESH
GVEFRYNTKVENVEFAIGGGDGPKREHTGVGQDTIQKIQATSGFFKRNPASTPTKKLAVR
IDVSQEGEKSSIDLTENDLVFITNGGCVENSTMGSQNSPAAWNPDLKPGGGWDMWRRIAE
QDPSFGHPEKFCSDPNATKWMSATVTTLDDEIPPYIQKICKRDPFSGKVVTGGIVTVQDS
NWLMSWTLNRQQQFRDQPKDQLCVWVYGLFPDKPGNYVKKPMTECTGEEICEEWLYHMGV
PTDKIESLAKHHANTVPVMMPYITAFFMPRAAGDRPDVVPDGAVNFAFLGQFAETPRDTI
FTTEYSMRTGMEAVYTLLGVDRGVPEVWGSVYDVRNLLNATVKLRDGAPVTDMKLNFIEK
AVVKKVLKKLDGTDIATLLREYHVI