Protein Info for BBR_RS16840 in Bifidobacterium breve UCC2003

Annotation: chromosome segregation protein SMC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1215 PF13175: AAA_15" amino acids 1 to 66 (66 residues), 36.9 bits, see alignment 1.1e-12 TIGR02168: chromosome segregation protein SMC" amino acids 2 to 1213 (1212 residues), 839.8 bits, see alignment E=1.8e-256 PF02463: SMC_N" amino acids 2 to 1206 (1205 residues), 242.8 bits, see alignment E=8.9e-76 PF13476: AAA_23" amino acids 5 to 200 (196 residues), 69.5 bits, see alignment E=1.9e-22 PF13555: AAA_29" amino acids 9 to 48 (40 residues), 27.1 bits, see alignment (E = 8.8e-10) PF13304: AAA_21" amino acids 26 to 225 (200 residues), 33.6 bits, see alignment E=1.2e-11 amino acids 1120 to 1185 (66 residues), 29.9 bits, see alignment 1.7e-10 PF06470: SMC_hinge" amino acids 509 to 624 (116 residues), 33 bits, see alignment E=2.1e-11

Best Hits

KEGG orthology group: K03529, chromosome segregation protein (inferred from 85% identity to bln:Blon_0891)

Predicted SEED Role

"Chromosome partition protein smc" in subsystem Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1215 amino acids)

>BBR_RS16840 chromosome segregation protein SMC (Bifidobacterium breve UCC2003)
MYLKELTLRGFKSFASATTLRFEPGITAVVGPNGSGKSNIVDALTWVMGEQGAKNLRGTS
MEDVIFAGTSSRPPLGRAQVSLTIDNSDHTLDIDYTEVTISRTIFRNGGSEYAINGSQCR
LLDIQELLSDTGLGQQMHVIVGQGRLDAILKADPSGHRAFIEEAAGILKHRKRKERALRK
LANTESNLNRLDDLLREIHRQLGPLGRQARISRRADAIQVSVRDAQARIYAEDAQRSMAR
RETVRKELGDVRSQLSVAQRELAQVKVRIEQVEALSSESSPAIAKTNQYWHEFSQIRERL
HALAQLAEERGHSLTGQIVSNFGEDPDMLLKRAKELETQAAAQTKAVADARIALDKATEE
RADDEKKLASIRQTLTELRKTAQERDAHIASLRELIAREESAVQLADSRAKDHTGQRETL
AKQHDDAQHQLESLRSEAQSVADDDGAALDKARAALAERRDVLNELTDRQRDVQSKIISL
QAKADALSDTLDSRNASGSLERDEQVASLGRLTDFIHVADGWEEAVAHALDQYASAIVVP
ETGNMLHALERAREDKLGKAVVLTVMPADEPFAALADTDICLANLVTANPEASDKTQAAA
CVRTVQLLLADVAAAETADEAQRLVASGKAPRAVTKHGETFAHGVAAVGGSSISQSDLSL
AARRDKALAQVKQLGVEANELAEQVSEAKSKRDEAARLVDQESAKRTEVRLKAQQAEKSL
KSAEDRVASFARQLEQLDKKIADTQENRNEHQLKLDDLNRALESAQQSTDEHADFDELDE
RERTLERDLNLTREHEVAAKIAWTEASRKGESLTRQAGLLRDNAKEAVERRARIESLNER
RRDQAAHLQGVADDAREVAAMVERTLQGVAAERDKLQEAASSHDDELKTLRAQRNEIEPK
VTDLTGREHALDVNRERLAAEAGQLMQKVSDELGLTLEELVREYGPDQPVPVLDDDGNPV
PLEHMDGEGDGNADDAATDAPDAAANSVTDPSRFQTVPYNRQEQQKRLDKARRDLAALGK
INPLATEEFEALEERNKYLNDQRNDVVKSRDDLMQLIKDLDSTMVEVFKSAFDDTAEAFE
KMFATLFPGGTGRLRLENPEDLLTTGVLVEASPAGKRVKQLSLLSGGERSLTALALLFAI
FTARPSPFYVMDEVEAALDDVNLTRLIDAFNELRAHAQLIIITHQQRTMSIADALYGVTM
RADGVTAVVSQKLDK