Protein Info for BBR_RS16795 in Bifidobacterium breve UCC2003

Annotation: Cys-tRNA(Pro) deacylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 168 TIGR00011: Cys-tRNA(Pro) deacylase" amino acids 13 to 165 (153 residues), 177 bits, see alignment E=1.1e-56 PF04073: tRNA_edit" amino acids 45 to 156 (112 residues), 74.7 bits, see alignment E=3.5e-25

Best Hits

Swiss-Prot: 48% identical to YBAK_ECOLI: Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK (ybaK) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 95% identity to bln:Blon_0899)

MetaCyc: 48% identical to Cys-tRNAPro/Cys-tRNACys deacylase YbaK (Escherichia coli K-12 substr. MG1655)
3.1.1.M26 [EC: 3.1.1.M26]

Predicted SEED Role

"Cys-tRNA(Pro) deacylase YbaK"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.1.M26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (168 amino acids)

>BBR_RS16795 Cys-tRNA(Pro) deacylase (Bifidobacterium breve UCC2003)
MAKKKHDKGAGSTPATVQLEKADVEFHVYEYEHSNDHMDDGYGVEAATKLGFDEHQVFKT
LMADTGSERVVGVVPVSGHMDLKALAAAAGAKKASMADPKVAMRESGYVVGGISPLGQKT
HHKTVLDESALQFDQILVSGGKRGLSVGVNPQDLLKVLDAVAAPIGTW