Protein Info for BBR_RS16465 in Bifidobacterium breve UCC2003

Annotation: ribokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00294: PfkB
  • amino acids 28 to 318 (291 residues), 193.2 bits, E=7e-61

Best Hits

Swiss-Prot: 38% identical to RBSK_SCHPO: Ribokinase (rbk1) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: K00852, ribokinase [EC: 2.7.1.15] (inferred from 92% identity to bln:Blon_0963)

Predicted SEED Role

"Ribokinase (EC 2.7.1.15)" in subsystem D-ribose utilization or Deoxyribose and Deoxynucleoside Catabolism (EC 2.7.1.15)

MetaCyc Pathways

• 2-deoxy-D-ribose degradation I (2/3 steps found)
• ribose phosphorylation (1/2 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.15

Use Curated BLAST to search for 2.7.1.15

Protein Sequence (330 amino acids)

>BBR_RS16465 ribokinase (Bifidobacterium breve UCC2003)
MVISEEEHEQMPEPVREGLEALKDAQGSVIVIGSMNADYTVTTKRLPKPGETVQGGAMKV
MPGGKGANQASAAARLGLNVQLLGAVGDDANADFLLSKLDEAGVDTADILHVEGPSGTTV
ITVSAEGENTIVYSPGANSKAAAGYVQSHRLTIAGCSVLGLCLESPISTVVAAAQTAHDA
GVTVLLNDSPFMDELPHELVEVTDILLVNQHEVAQLLGLPDGDVESLDWYEVAERFTDYG
FDRAIVTLGASGSVVIENGRWHRVSAAQVKAVDTTGCGDSFMGTVLAGLAAGYTLLQSAQ
IGSYVSAYAATKIGAQSAYGTADEVIAYFS