Protein Info for BBR_RS16320 in Bifidobacterium breve UCC2003

Annotation: metal-independent alpha-mannosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 PF06824: Glyco_hydro_125" amino acids 28 to 423 (396 residues), 520.3 bits, see alignment E=1.9e-160

Best Hits

KEGG orthology group: K09704, hypothetical protein (inferred from 97% identity to blb:BBMN68_225)

Predicted SEED Role

"narrowly conserved hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (432 amino acids)

>BBR_RS16320 metal-independent alpha-mannosidase (Bifidobacterium breve UCC2003)
MTTTAIPKSVSDFMQHITDLCGTEHAAWAENFNACFANTLTTTVKRHDDGTTFLLTGDIP
AMWLRDSTAQLRPYLALAAEDGDIASLIAGLVRQQFRYITIDPYANAFNEEPNGASWDKD
DQSDFSSPWLWERKYEVDSLCYPIQLAWMLYANTGNTDHFDAEFIAGVKKILDVFETEQH
HERSPYFFIRDTDIPTESLSNDGKGSPVAYTGMTWSGFRPSDDACTYHYLVPSNMFAAVV
MGYLERIFSGEILNDADIAARAGELRRTITEGIEAHAKTTSRNGETIYAFETDGLGHVNI
MDDSNVPSLMAAPYLGYCAPDDPTYLATRRTLLSDENPYYYEGEYLKGIGSPHTPPRYVW
PIALSIEAMTSDSKDFKAHILDRLVATDAGTHLMHEGIDVDDPTKYTREWFSWSNMMFCE
LVMDYFDIRVKH