Protein Info for BBR_RS16135 in Bifidobacterium breve UCC2003
Annotation: peptide deformylase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 94% identical to DEF2_BIFLO: Peptide deformylase 2 (def2) from Bifidobacterium longum (strain NCC 2705)
KEGG orthology group: K01462, peptide deformylase [EC: 3.5.1.88] (inferred from 94% identity to blb:BBMN68_370)Predicted SEED Role
"Peptide deformylase (EC 3.5.1.88)" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases or Conserved gene cluster associated with Met-tRNA formyltransferase (EC 3.5.1.88)
Isozymes
Compare fitness of predicted isozymes for: 3.5.1.88
Use Curated BLAST to search for 3.5.1.88
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-positive bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (161 amino acids)
>BBR_RS16135 peptide deformylase (Bifidobacterium breve UCC2003) MAIREIRVVPDPVLRTPCDEIKEITPAVRRLVDDLLETVDDPGRAGLSANQIGVSLRAFS YNIDGKVGYVLNPVLEEKSGEQYGDEGCLSVPGLWYKTRRAEYARVRGIDLDGKEVVLEG TGIMGRMLQHECDHLDGHVYLDRLEKEERRAAMKYMREHQK