Protein Info for BBR_RS15735 in Bifidobacterium breve UCC2003

Annotation: Helicase helY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 862 PF04851: ResIII" amino acids 49 to 196 (148 residues), 53.2 bits, see alignment E=6.8e-18 PF00270: DEAD" amino acids 50 to 200 (151 residues), 99 bits, see alignment E=5e-32 PF00271: Helicase_C" amino acids 383 to 465 (83 residues), 25.7 bits, see alignment E=2.3e-09 PF08148: DSHCT" amino acids 686 to 858 (173 residues), 124 bits, see alignment E=1.2e-39

Best Hits

KEGG orthology group: K03727, ATP-dependent RNA helicase HelY [EC: 3.6.4.-] (inferred from 93% identity to bll:BLJ_1029)

Predicted SEED Role

"FIG005666: putative helicase" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.-

Use Curated BLAST to search for 3.6.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (862 amino acids)

>BBR_RS15735 Helicase helY (Bifidobacterium breve UCC2003)
MARHPHHQEGDSSRTLSPAQRYASFQKANKHRASVAARFAATLPFDLDDFQTEANDALEA
GSNVLVAAPTGAGKTVVADFAIYLAQERNVKAFYTTPIKALSNQKYHDLVDVYGPDKVGL
LTGDTSINSEADIVVMTTEVLRNMLYEHSTTLTALRYVILDEVHYLADRFRGPVWEEVII
HLPKTVKIVGLSATVSNVEDFSNWIASVRGETKLVISEHRPVPLEQHVIVQADEQTEPEV
LDLYRRDGNGNQTTKLNAELINRLDQLDRKAARRRGEERPDKRRGFKGKGGKGHRDRVPR
PERHTPRRWAVVDELNFLGMLPGIYFIFSRNGCDQAVEQCINAGLELTTDEEVTRIRRIV
DEMVEGQLTQEDLKALQFSKFRFALEEGFASHHAGMIALFRQIVERLFEEGLVKMVFATE
TLALGINMPARCVVVEKLEKFDGTGHVGLTPGEFTQLTGRAGRRGIDTIGHAIVVDHHGF
VPATAAALSSKRVYPLHSSFRPTFNMAVNLLNSSDYGTARITLDQSFAQWEANESAWQLE
SQINTLTNALAGYEQAFACNHGDFKQFMTLRMELSDIEKDGRRKLKHEVFLTDQDRSRAF
QDLDKRIQKLRKAEHEHPCRNCPDLQQHLKWGHRWARETRELNRVKYRYDSRTGSVARQF
DHICDILTQLGYLERHDDGNGRIDVTLTEKGLLLRRIYSEHDLELCEALLAGTFDKLDAN
GLAAVLSSLVYEARRGSDGEPRHYPGGISGPIAIASSKLQGICADINILCEDHSLEEMHQ
PDFGIVDIMYEWADGGSLGACLYGTDMTGGDFVRTAKRLADVLQQIAVAQPLPFDGGERL
ADIAHEAADRVNRGVVAYSGVD