Protein Info for BBR_RS15215 in Bifidobacterium breve UCC2003

Annotation: MazG-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 PF03819: MazG" amino acids 59 to 134 (76 residues), 95 bits, see alignment E=1.4e-31

Best Hits

KEGG orthology group: K02428, nucleoside-triphosphate pyrophosphatase [EC: 3.6.1.19] (inferred from 82% identity to blm:BLLJ_0770)

Predicted SEED Role

"Nucleoside triphosphate pyrophosphohydrolase MazG (EC 3.6.1.8)" (EC 3.6.1.8)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.19 or 3.6.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (293 amino acids)

>BBR_RS15215 MazG-like protein (Bifidobacterium breve UCC2003)
MSKISGETGYHNSDYRLPGGFEHCSKLKPVVEAATALDRVKAVVDVLYSPGGCPWDGKQT
NESLLKNLLEETYEYIDAVETHDRDNMREELGDVLLQSVFQARVCESDAEDPFDIDEVAD
RLVNKLITRHPHVFAADDAADSSDDDGKDGGAASQTESSEAVLALWEKMKQREKHRKSVL
EGISRAQGALPRAAKVVSRISKSPNADELFAAFVDSSSASTQQDVEQTQAANQSESNGGN
SVERGKADAYADEIFAIVREARTDGIDIEAALRNRLRDIEEKVVQIESEINNG