Protein Info for BBR_RS15175 in Bifidobacterium breve UCC2003

Annotation: GTPase Era

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 TIGR00436: GTP-binding protein Era" amino acids 28 to 318 (291 residues), 203.9 bits, see alignment E=3.1e-64 TIGR00231: small GTP-binding protein domain" amino acids 29 to 197 (169 residues), 65.5 bits, see alignment E=4.8e-22 PF01926: MMR_HSR1" amino acids 30 to 132 (103 residues), 80.5 bits, see alignment E=3e-26 PF02421: FeoB_N" amino acids 30 to 86 (57 residues), 36.4 bits, see alignment E=1.1e-12 PF07650: KH_2" amino acids 240 to 324 (85 residues), 42.8 bits, see alignment E=1.1e-14

Best Hits

KEGG orthology group: K03595, GTP-binding protein Era (inferred from 94% identity to bln:Blon_1581)

Predicted SEED Role

"GTP-binding protein Era" in subsystem Bacterial Cell Division or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (335 amino acids)

>BBR_RS15175 GTPase Era (Bifidobacterium breve UCC2003)
MDDRNISNDGDAAAASESVRQEVPYRSGFVAVVGRPNVGKSTLINALIGKQIAIASSRPE
TTRKAIRGILTTDNAQLVLVDTPGIHRPRTLLGQRLNDVVEESLSDVDVVAFLLPADQEI
GPGDKRILSRLRTDFATKREDGSFAWRIPLIAIVTKIDELGRQQLINKLIEINEFADFAD
IVPVSALKHDNLAEVRNVLIDHTPEGPQMYPDDQISEERPEDTIAELVRGAFLETLDDEL
PHSLAVVVDSIDYPEDNETGQGYDGKAQVNVSIYVERDSQKPIIIGKGASNLTYVKKKLR
TPVNRIVGQKAKLDLHVKVAKGWQSDPKQLERLGF