Protein Info for BBR_RS14960 in Bifidobacterium breve UCC2003

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 273 PF12146: Hydrolase_4" amino acids 18 to 252 (235 residues), 62.3 bits, see alignment E=1.1e-20 PF12697: Abhydrolase_6" amino acids 19 to 257 (239 residues), 73.8 bits, see alignment E=8.1e-24 PF00561: Abhydrolase_1" amino acids 19 to 138 (120 residues), 49.3 bits, see alignment E=1.4e-16 amino acids 190 to 253 (64 residues), 27.5 bits, see alignment E=6.2e-10 PF08386: Abhydrolase_4" amino acids 204 to 263 (60 residues), 25.1 bits, see alignment E=3.9e-09

Best Hits

KEGG orthology group: None (inferred from 94% identity to blm:BLLJ_0725)

Predicted SEED Role

"hydrolase, alpha/beta fold family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (273 amino acids)

>BBR_RS14960 alpha/beta hydrolase (Bifidobacterium breve UCC2003)
MAQPQPYYAIEGNDNGLSVVFVHGMGVDHRSLMMLDEAFDGNDSIRRIYLDLPGFGRTPA
LPENACGLPEMADWLQTVIDGLVGKATPFAMVGNSMGGALVREVLAREPRQVAGMALIAP
VVDPQHAGRHVAEHVVANPNPRLTHSLPQEQVFDFITMGVNQSFDAWRRYQRFILPGVAL
CDRAACERLDQRYWLYDDPEKTLGTYAGPVLIVTGKQDQIVGYEDQQALLPHYPNATFVT
LDNAGHNAHIDQPEAVITLVREWVAHMAFAPLR