Protein Info for BBR_RS14880 in Bifidobacterium breve UCC2003

Annotation: ATP-dependent helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 675 PF00270: DEAD" amino acids 51 to 246 (196 residues), 135.8 bits, see alignment E=1.2e-43 PF00271: Helicase_C" amino acids 290 to 388 (99 residues), 88.8 bits, see alignment E=3e-29

Best Hits

KEGG orthology group: None (inferred from 83% identity to blm:BLLJ_0708)

Predicted SEED Role

"ATP-dependent RNA helicase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (675 amino acids)

>BBR_RS14880 ATP-dependent helicase (Bifidobacterium breve UCC2003)
MPRNDFDDFEDSADFPMNDGEEFKPITFGELGVPGLLVRVLAADGKKTAFPIQADTLPDS
LAGRDVLGRGRTGSGKTLAFSIPLVTRLGSYDSLGQTAMKEFRDEIKRRKKASLEERRSD
DFLPHPRGLVLAPTRELANQINDVLMPLAHAFGMNTTTIYGGVKYIHQVRDLKAGTDIVV
ACPGRLEDLLRQKALTLSSVEVVVIDEADEMADMGFLPPVKRLLEQISPNAQHMLFSATL
DHGVDEVVNTFLHDPKVHEVDSATAEPDLMTHHVFETTRGDKHELVRTLASGTGRRILFT
RTKFQAKKLAKNLTQNGIPAAELHGNLSQNQRDRNLAAFDSGDVRVMVATDVAARGIDVG
GVELVVQVEPPADPKSFVHRSGRTARAGKAGDVVTLVLPEQRRETRRLLNQAGIKTKMIE
VTHDSPEVLELVGDRAERVDGWSLDKSQPVDNPRKGKNKGAKNAASGESGRGGKRKRNRN
RSRDEQNVIETETRYENVDGESYDDQPQHKHGGKANKKAMKKNRNRAERRAGMSNPEAER
RDYLFEHGDERRGNRREDRADTRYEDRRDRRRGKKSDDRYDDRRGDKYSKNGKSNRRDRF
DYDRSDEFGSRKHEGSKRIHRKNENRIVRDERSEGAKRHERRMIAKYGNTQGPKRHHSKK
NSSPFRSSGTRNGRR