Protein Info for BBR_RS14795 in Bifidobacterium breve UCC2003

Annotation: N-acetylglucosamine-6-phosphate deacetylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01979: Amidohydro_1
  • amino acids 79 to 398 (320 residues), 58.2 bits, E=4.5e-20

Best Hits

KEGG orthology group: K01443, N-acetylglucosamine-6-phosphate deacetylase [EC: 3.5.1.25] (inferred from 76% identity to bbp:BBPR_0567)

Predicted SEED Role

"N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)" in subsystem Chitin and N-acetylglucosamine utilization or Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 3.5.1.25)

MetaCyc Pathways

• superpathway of N-acetylneuraminate degradation (17/22 steps found)
• N-acetylglucosamine degradation II (3/3 steps found)
• N-acetylglucosamine degradation I (2/2 steps found)
• superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation (4/6 steps found)
• D-galactosamine and N-acetyl-D-galactosamine degradation (1/4 steps found)
• N-acetyl-D-galactosamine degradation (1/5 steps found)
• chitin derivatives degradation (3/8 steps found)
• peptidoglycan recycling I (7/14 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Galactose metabolism
• Nucleotide sugars metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.25

Use Curated BLAST to search for 3.5.1.25

Protein Sequence (414 amino acids)

>BBR_RS14795 N-acetylglucosamine-6-phosphate deacetylase (Bifidobacterium breve UCC2003)
MDRQQIVAQVTDSMEGAPSAFAIRDARKVDARGIEEHAWIVADANGAIAARGTSDDDFEA
ACRANGIGTDAVIDASGKIMTPGYVDIHSHGAWEKSFDDGPDGIDVARAGHAMHGTTRQV
CSLITNPIDVQCENLRNVRAKMDQRPDILGAHLEGPFLALSRKGAHDPECLKDPVPEIVD
RMLEAADGCLRQITIAPELPHGLQAIRSFATVGTVPAVGHCDADYETARRAFDEGAGLMT
HMFNAMNGLHHRKPGPIPAAVEDPRVTIELICDGFHVQDPMLRLGLGFAPHRIAFVTDAM
AATDCPDGAYKLGALDVDVVDGHARLKSNGAIAGSTLTLEHAVQRAVLELGMSPVEAIEA
ATLTPARAFGFDRPYPVTGAPLGLLAPGYAADVLLTDPADWSVQHAWCAGRRIK