Protein Info for BBR_RS14670 in Bifidobacterium breve UCC2003

Annotation: excinuclease ABC subunit UvrA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 747 PF00005: ABC_tran" amino acids 461 to 666 (206 residues), 48.9 bits, see alignment E=3.3e-16

Best Hits

KEGG orthology group: None (inferred from 99% identity to bln:Blon_1685)

Predicted SEED Role

"Excinuclease ABC subunit A paralog of unknown function" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (747 amino acids)

>BBR_RS14670 excinuclease ABC subunit UvrA (Bifidobacterium breve UCC2003)
MADIMVYGLTQNNLKHVTFRIPKEKITVFTGVSGSGKSSIVFDTIAAESQRQMNLTYPAF
VRSRLPKYPRPAVERIDNLTPSVVVDQSSLGGNARSTVGTISGLYASLRLLFSRIGQPFV
GTASYFSFNDPNGMCKTCSGLGKVTKVDMEAVLDRNKSWNQGCVKDSLYRPGSWYWKQYA
ESGLFDLDKPIRDYTKEEYNLLVYGARDGKGEPENPKVTGLYHKYTKALLNRDISSKSRH
TKEKSKKLITEIECSDCHGRRLNEAALNCRINGYSIADMCEMELTLLREVLTQITDQTVG
LLVHTILEGLDRMIEIGLPYLHLNRETPSLSGGEAQRLKLVRYMGSSLTGMTYIFDEPSA
GMHPRDVYRMNHLLKKLRDKGNTVLVVEHDKDVISIADHVIDVGPAAGQNGGEIVFEGSY
PELLRTDTLTGKSMQKLFPIKQTPRKATGSLPVRDACLHNLKHVDVDIPLGVMTVVTGVA
GSGKSTLISQVFARAYENEVVMVDQGPITATSRSTPASYLGFFDEIRKLLARENNQPESL
FSFNSAGACPICGGKGVLVTELAFMDPIVTECEACGGVRYNREALACTYKGRNIVQLLGL
TASQALELFEDTRIRKRLSVMQQVGLSYLTLGQPLSTLSGGERQRIKLAKNLGKSGSIIV
MDEPTTGLHRSDVDNLLKLFDGIVSSGNTLVVIEHNLDVMKQADWIIDIGPDGGKNGGEV
VFTGTPEEMLQNAKTLTADCLRASSIS