Protein Info for BBR_RS14450 in Bifidobacterium breve UCC2003
Annotation: methionine ABC transporter ATP-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 91% identical to METN_BIFLO: Methionine import ATP-binding protein MetN (metN) from Bifidobacterium longum (strain NCC 2705)
KEGG orthology group: K02071, D-methionine transport system ATP-binding protein (inferred from 91% identity to blj:BLD_0698)Predicted SEED Role
"Methionine ABC transporter ATP-binding protein" in subsystem Methionine Biosynthesis or Methionine Degradation
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-positive bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (400 amino acids)
>BBR_RS14450 methionine ABC transporter ATP-binding protein (Bifidobacterium breve UCC2003) MSDPIITFDHVVKEFKIRGRKAETARAVNDVSLSIDRGDIFGIIGYSGAGKSTLVRLINA LERPTSGTVTVLGTDITALNESKLRPIRQKIGMIFQQFNLFSTKTVSQNIAYPLQLDHWR KDYQDRRVKELLEFVGLAEHADKYPSQLSGGQKQRVGIARALATNPEILLADEATSALDP ETTTEVLALLKRVNEEFGITIVLITHQMNVVQQIANRVAVMSSGRVVESGDVYDVFAAPR QPVTKRFIATALSGLPEESRVERLHGEWSGRIVTVLIRQKDVSDDHGRTLHASGQNISEL IAKYGVESSLLYGGIDTVKGSAIGAITYEFNGPGWHVDEFLRELAQHSDVIDFGTAEKPV AYADAVANHIAGAEAAIANQQSVSQDESAEISASHEGANA