Protein Info for BBR_RS14100 in Bifidobacterium breve UCC2003

Annotation: UPF0182 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1085 transmembrane" amino acids 72 to 94 (23 residues), see Phobius details amino acids 117 to 139 (23 residues), see Phobius details amino acids 172 to 190 (19 residues), see Phobius details amino acids 227 to 253 (27 residues), see Phobius details amino acids 275 to 295 (21 residues), see Phobius details amino acids 315 to 339 (25 residues), see Phobius details amino acids 360 to 385 (26 residues), see Phobius details PF03699: UPF0182" amino acids 75 to 902 (828 residues), 863 bits, see alignment E=9.7e-264

Best Hits

Swiss-Prot: 91% identical to Y1029_BIFLO: UPF0182 protein BL1029 (BL1029) from Bifidobacterium longum (strain NCC 2705)

KEGG orthology group: K09118, hypothetical protein (inferred from 92% identity to blb:BBMN68_776)

Predicted SEED Role

"INTEGRAL MEMBRANE PROTEIN (Rhomboid family)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1085 amino acids)

>BBR_RS14100 UPF0182 family protein (Bifidobacterium breve UCC2003)
MSFNDPFSILFGNGGGSRRNNSNDDDPIILNVEADGDTPNRNGSNPSGRGPAGPRLPRRP
SGSHGNSRGTKIFIGVVLALVIIVALFFGLSRFITDLMWYGQLGFQSVVWTQFGVKIGLW
VAYALLMALTGFIAAWLAIRARPDSADGSTIRINGDVVEVGKSASSKTARRVAVVISLIV
GVIFGSQFNANWSEILLMFNAQKFGTTDPQFGLDNGFYVFVLPGLKLVLAAVAMLLGVGL
VFSLVTHVLMGGIRITMPVNGRGLFSITKRARRQLGIWLILNMLAWSVRQVLGVFEQLTV
QGSRITGASYTAVHANIPVTFIMAALTAILGVVLGVWLMRSHALEGQASIGVRASAALKA
WRVPVIAIAATVVVGMVLTIAWPMLLQRFRVNPNAQEMESTYIQRNIDATRAAYGLDKLK
TEQYKVTDKGEQGALAKEADTTAQIRLLDPQVVSPTFKQLQQSKQYYTFADTLAVDKYEI
DGISQDTVIAARELDLAGNDNRNWVNDHTVYTHGYGVVAAYGNKVTADGQPEFFESGIPT
QGKLTESEKYEPRIYFSPNTTEYSIVGAPEGTQAWEFDYPTGSEGALTTFKGDGGPSVGN
LFSRILYAIRFGSDQILFSDRVTSESQILYDRSPKERVAKVAPYLTLDGRVYPAVVDGRV
KWVVDGYTTSDAYPYSQMTDLGNATKDSTTVSSSTVSSLGSQQANYIRNSVKATVDAYDG
SVDLYVWDQSDPVIKAWEKIFPGQYHQLSEISGDLMSHLRYPESLFKVQRELLSKYHVTS
ANQYYSGEDFWQTPVDPTESQSQQDQDILQPPYYLTLQTGGTKAPVFSLTSTYIPAGQST
REILTGFLSVDSDAGGEKGKIGPNYGTIRLQELPKDSNVPGPGQAQNNFNANADVSKELN
LLQSGDTQVVRGNLLTLPLGGGLVYVQPVYVKSSGATSFPLLKKTLVAFGDQVGFADTLD
EALDQVFGGDSGAAAGDAENVSGDGSSDSSNTGGQDASNQSGSDTSGDQSQSDGQSGTTD
GKSDSGTSSGQSGTARSPELQQALNDAAQAMKDSQSAMKNGDWTAYGKAQQQLEEALNKA
IELDK