Protein Info for BBR_RS13855 in Bifidobacterium breve UCC2003

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 490 PF00005: ABC_tran" amino acids 25 to 172 (148 residues), 83.8 bits, see alignment E=5.5e-27 amino acids 289 to 440 (152 residues), 100.2 bits, see alignment E=4.8e-32

Best Hits

KEGG orthology group: K02006, cobalt/nickel transport system ATP-binding protein (inferred from 92% identity to blf:BLIF_0565)

Predicted SEED Role

"Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine" in subsystem ECF class transporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (490 amino acids)

>BBR_RS13855 ABC transporter ATP-binding protein (Bifidobacterium breve UCC2003)
MQVDPAAVEASGWGWRHATRKDFALRAVDFTIRPGERVLLLGASGAGKSTMMAGLAGVLG
GDEEGEQEGSLTIDGVDAREARGRVGLVLQDPDSQIILERLGDDAAFGCENLNVPREEIW
QRVRESLDMVGLGGLELGRSTRHLSGGQRQRLALAGVLAMKPGLLLLDEPTANLDPEGVI
EVHDAVKKVIETTGQTMVVVEHHIDVWLDLVDRVIVLGRPDADSPAGAVIADGKPDEVFA
QMGDVLAAGGAWVPGRAIPDYRPDDETRGETVLSTENLSFGRGTALGTGINLDFHAGEVT
ALMGPNGAGKSTMALTLAGLLKPIDGKVLIADSLKPPHAGQEPINWKSKELLGRIGMVFQ
EPEHQFASNFVRDEVAIGPKSMGHSEDEAYQTADRMLDQMNLTRFAKANPYTLSGGEKRR
LSVASMLAAAPKVLVMDEPTFGQDFSTWTEMVKLIAAIRDQGSCVIMVTHDEALVDALGA
RRVMFEETRA