Protein Info for BBR_RS13850 in Bifidobacterium breve UCC2003

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 199 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 54 to 71 (18 residues), see Phobius details amino acids 78 to 95 (18 residues), see Phobius details amino acids 101 to 120 (20 residues), see Phobius details amino acids 125 to 145 (21 residues), see Phobius details amino acids 157 to 177 (21 residues), see Phobius details PF09819: ABC_cobalt" amino acids 15 to 137 (123 residues), 134.2 bits, see alignment E=1.3e-43

Best Hits

KEGG orthology group: None (inferred from 94% identity to bln:Blon_1888)

Predicted SEED Role

"Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine" in subsystem ECF class transporters or Thiamin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (199 amino acids)

>BBR_RS13850 ABC transporter permease (Bifidobacterium breve UCC2003)
MAEAVAKVNYKWRVVDIVVAAILAVASGVIFWGWDIVCTAPLTLFEGVTPGFEGLLNGFW
LFAGPLAAIIVRKPGAALFAETLAAFLELTLGNQWGVGGSLIVGIIQGLGAEIGFAVFAW
KKWNLGTTILSGALAGVGCWAYYWATNPGWNAMRVTWYLVGSIISGIVIAGVVVWYLSRA
LAATGALERFESGRSKARV