Protein Info for BBR_RS13790 in Bifidobacterium breve UCC2003

Annotation: pyridoxal phosphate-dependent aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: None (inferred from 57% identity to gvg:HMPREF0421_20798)

Predicted SEED Role

"Cystathionine beta-lyase, type II (EC 4.4.1.8)" in subsystem Methionine Biosynthesis (EC 4.4.1.8)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.4.1.8

Use Curated BLAST to search for 4.4.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (403 amino acids)

>BBR_RS13790 pyridoxal phosphate-dependent aminotransferase (Bifidobacterium breve UCC2003)
MSVHFSSRVDISDPNPIAAAEAAARANGTALGKLNDSNPTRHGLAPALVPSVYTADPRGS
YAVREALAAFLNEANADRSQMNASANTASRGVKPEQLYVLSSTSEAYSWLIKLLCDAGDA
VLAPKPGYPLIESIARLECVDTVEYQLRFDGSWFIDVAELEQLLDGLSGARIRALVLINP
NNPTGSYVKPAERERIVTMCRERGIALIADEVFFDYALEPFAGNARLAGEQGVLTFALDG
FSKMLAAPHAKVGWIQVSGPAEDVAQAQRRLDVIADDYLPMSDIIAQRIPALLEAATEQT
ARVEERVRGNLATLHELLDADPNGLVSVLRAEGGWNVLLRVPSVIDENEMVLKLIAEHGL
TGQPGYFFDMTSNGYLAVSLLPEPEVFRQGICAVLATVEALLA