Protein Info for BBR_RS13735 in Bifidobacterium breve UCC2003
Annotation: Lon protease
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K07177, PDZ domain-containing protein (inferred from 84% identity to bll:BLJ_1376)Predicted SEED Role
"Lon-like protease with PDZ domain" in subsystem Proteasome bacterial
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-positive bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (307 amino acids)
>BBR_RS13735 Lon protease (Bifidobacterium breve UCC2003) MEAHPEHDDSAASSSNSSKETGQSRFSRAAQRVRRYLAARSPRHFIGAFAVLLGVVILLL PSPYVIEGPGPTQNVLGSVEDGAVIDVSGKGVSTYQDSGSLLLTTVNASGVPGYTIINAQ AVWAWANPKMEIMPREATVPVGQTADEYQKTVDKDMAGSQSSASEVGLAYAKAHADELGI DAASLAHAKVTMHVDSIGGPSAGMMYTLGLIDKLTPESESGGKTIAGTGTIDKKGNVGKI GGIQLKMLGAKRDGATWFLAPADNCSEVAGHVPDGLRDVKVATLDEAYQALVAIGKGQAD DLPHCTA