Protein Info for BBR_RS13555 in Bifidobacterium breve UCC2003

Annotation: excinuclease ABC subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 834 PF17755: UvrA_DNA-bind" amino acids 186 to 255 (70 residues), 44.3 bits, see alignment E=4.9e-15

Best Hits

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 96% identity to blm:BLLJ_0529)

Predicted SEED Role

"Excinuclease ABC subunit A paralog of unknown function" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (834 amino acids)

>BBR_RS13555 excinuclease ABC subunit A (Bifidobacterium breve UCC2003)
MSNDQRPQAIEVRGARVHNLKNIDIDIPLGELVGVAGVSGSGKSSLALGVLYAEGSRRYL
EALSTYTRRRLTQASRAQVDEVLHVPAALALHQRPTVPGIRSTFGTMTELLNSLRLLFSR
VASHVCPHCGARNESTLNVAAGLPITCAGCGKEFHAPGAESLAFNSAGACPTCSGTGIVR
EVNRAALVPDESKSIDDGAVLPWGSLMWDLMKQVCGAMGVRTNVPFSELTPEERDIVFNG
PAIKKHILYKPKKGDDFAELDFTYFNAVYTVENALAKAKDEKGLKRVARFLKEGPCADCG
GTRLSAAARAPHVRGLNLAEASAMTLDTAVDWVRGVPESLPADMRPMATNICESFLNVAR
RLLDLGLGYLALDRAGATLSTGERQRVQLARAVRNRTTGVLYVLDEPSIGLHPSNVDGLL
GVMRDLVADGNSVVVVDHDVRVLKAAGHLIEMGPVAGAEGGHVIAQGTVDEVAANPSSRI
APFLADNVSARIRERVAESQVFDLGHIRMTTSQLHTVKPLDVDIPRGRLVAVTGVSGSGK
TTMVLESLIPALKAQAVGERLPEHVRELEAEGIHRANLIDATPIGANVRSTVATYADIHD
ELRRAFARCDAAKTGGWKAGDFSYNTGRLRCPTCDGTGSISLDVQFLPDVTIECPDCGGS
RYASEAGAIRRAVKGESHLSLSLPQLMAMSVDQALAVTHDLKKVHARLTTLHDLGLGYLT
LGEPTPALSGGEAQRLKLASEMGKAQSDAVFVFDEPTIGLHPLDVRVLLGVFDRLVASGA
TVVVIEHDLDVIANADWIIDMGPGGGESGGRIVATGTPEQVAANPSSITGRYLG