Protein Info for BBR_RS13495 in Bifidobacterium breve UCC2003

Annotation: elongation factor G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 707 TIGR00484: translation elongation factor G" amino acids 6 to 705 (700 residues), 1069.7 bits, see alignment E=0 PF00009: GTP_EFTU" amino acids 10 to 291 (282 residues), 211.7 bits, see alignment E=1.8e-66 TIGR00231: small GTP-binding protein domain" amino acids 12 to 189 (178 residues), 122.8 bits, see alignment E=1.2e-39 PF03144: GTP_EFTU_D2" amino acids 334 to 401 (68 residues), 58.3 bits, see alignment E=2e-19 PF14492: EFG_III" amino acids 414 to 487 (74 residues), 111.6 bits, see alignment E=3.8e-36 PF03764: EFG_IV" amino acids 489 to 611 (123 residues), 145.9 bits, see alignment E=1.2e-46 PF00679: EFG_C" amino acids 614 to 699 (86 residues), 103.8 bits, see alignment E=1e-33

Best Hits

Swiss-Prot: 98% identical to EFG_BIFLD: Elongation factor G (fusA) from Bifidobacterium longum (strain DJO10A)

KEGG orthology group: K02355, elongation factor G (inferred from 98% identity to blj:BLD_0853)

Predicted SEED Role

"Translation elongation factor G" in subsystem Translation elongation factor G family or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (707 amino acids)

>BBR_RS13495 elongation factor G (Bifidobacterium breve UCC2003)
MAEEISDLHDVRNIGIMAHIDAGKTTTTERILFYTGKNYKIGETHDGASTMDFMAQEQER
GITIQSAATTCFWSRQSHDTKGKFQINIIDTPGHVDFTAEVERSLRVLDGAVAVFDGKEG
VEPQSETVWRQADKYGVPRICFINKMDKLGANFYYSVDTIKEKLGATPIVMQLPIGSEND
FTGVVDLVEMQAYVWNGTEELGAKYDTTEIPDDLKDKAQEYHEKLVEAAAEADDELMNKF
FEDGDLSKEDIRAGVRKLTIAKEAFPIFCGSAFKDKGVQPMLDGVVDYLPSPEDVPAIKG
YKPGDESVEIDRKPVKTDPFSALVFKISTHPFYGKLVFVRVYSGSVKPGDSVLDSTREKK
ERIGKIFQMHADKENPMEQADAGNIYTFVGLKNVTTGDTLCAIDDPITLDSMTFPDPVIQ
VAVEPKTKADQEKMGIALSKLAEEDPTFQVTTDEESGQTLIAGMGELQLDIIVDRMRREF
KVECNQGKPQVAYRETIRKAVMDQGYTHKKQTGGSGQFAKVLMDFEPLDTTEGKTFEFEN
KVTGGHISGEFIGPIEAGVKEAMESGILAGFPVVGVKATVTDGQMHPVDSSEMAFKLAGS
MCFKEAAPKAKPVILEPIMKVEVRTPEEYMGDVIGDLNQRRGNIQSMTDGVGVKVIDAKV
PLSEMFGYIGDLRSKTQGRAMFTMEMDSYDEVPKSVSEEIIKAQRGE