Protein Info for BBR_RS13335 in Bifidobacterium breve UCC2003

Annotation: transcriptional repressor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 PF01475: FUR" amino acids 11 to 125 (115 residues), 97.3 bits, see alignment E=3.7e-32

Best Hits

KEGG orthology group: K03711, Fur family transcriptional regulator, ferric uptake regulator (inferred from 99% identity to bln:Blon_1974)

Predicted SEED Role

"Zinc uptake regulation protein ZUR" in subsystem Oxidative stress or Transport of Zinc

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (166 amino acids)

>BBR_RS13335 transcriptional repressor (Bifidobacterium breve UCC2003)
MSIEQTATTRRVTRPRLLITQVLAELSRFATAQEITDILRERGTRIGTATAYRNVQMMAS
QGELDVIHVNGEALYRECSDQHHHHHIVCHECGRTIEIEIPGLEQWIDKAAKQLKYQTIA
HELEIFDLCPKCAAKHAIEPPLSVGTSPKDGPLTTPDDTGRRRSNK