Protein Info for BBR_RS13250 in Bifidobacterium breve UCC2003
Annotation: alpha-glucosidase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01182, oligo-1,6-glucosidase [EC: 3.2.1.10] (inferred from 81% identity to blf:BLIF_1936)Predicted SEED Role
"Oligo-1,6-glucosidase (EC 3.2.1.10)" in subsystem Maltose and Maltodextrin Utilization (EC 3.2.1.10)
MetaCyc Pathways
- sucrose degradation III (sucrose invertase) (4/4 steps found)
- sucrose degradation V (sucrose α-glucosidase) (3/5 steps found)
- starch degradation I (1/3 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.2.1.10
Use Curated BLAST to search for 3.2.1.10
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-positive bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (604 amino acids)
>BBR_RS13250 alpha-glucosidase (Bifidobacterium breve UCC2003) MTSFNREPLPDAVRTNGATPNPWWSNAVVYQIYPRSFQDTNGDGLGDLKGITSRLDYLAD LGVDVLWLSPVYRSPQDDNGYDISDYRDIDPLFGTLDDMDELLAEAHKRGLKIVMDLVVN HTSDEHAWFEASKDKDDPHADWYWWRPARPGHEPGTPGAEPNQWGSYFGGSAWEYSPERG EYYLHQFSKKQPDLNWENPAVRRAVYDMMNWWLDRGIDGFRMDVITLISKRTDPNGRLPG ETGSELQDLPVGEEGYSSPNPFCADGPRQDEFLAEMRREVFDGRDGFLTVGEAPGITAER NEHITDPANGELDMLFLFEHMGVDQTPESKWDDKPWTPADLETKLAEQQDAIARRGWASL FLDNHDQPRVVSRWGDDTSKTGRIRSAKALALLLHMHRGTPYVYQGEELGMTNAHFTSLD QYRDLESINAYHQRVEETGIRTSETMMRSLARYGRDNARTPMQWDDSTYAGFTMPDAPVE PWIAVNPNHTEINAADETDDPDSVYSFHKRLIALRHTDPVVAAGDYRRVETGNDRIIAFT RTLDERTILTVINLSPTQAAPAGELETMPDGTILIANTDDPVGNLKTTGTLGPWEAFAME TDPE