Protein Info for BBR_RS13065 in Bifidobacterium breve UCC2003

Annotation: amino acid ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 PF00005: ABC_tran" amino acids 40 to 202 (163 residues), 123.8 bits, see alignment E=8.3e-40

Best Hits

KEGG orthology group: K02028, polar amino acid transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 94% identity to bll:BLJ_0510)

Predicted SEED Role

"ATP binding protein of ABC transporter"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.21

Use Curated BLAST to search for 3.6.3.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (276 amino acids)

>BBR_RS13065 amino acid ABC transporter ATP-binding protein (Bifidobacterium breve UCC2003)
MTMNDITSVVPAVHKAADGSVIPAVKAVQVHKAFGPLHVLKGIDLTVMPGTVTVILGPSG
SGKSTFLRLINQLETLTGGSIEVDGELIGYKHVTKNGQDVLQTLDDKEIAAQRSRLGMVF
QRFNLFPHMTALENVMEAPVHVQHKSKSEARALAEAELQRVGLGDRMDYYPSQLSGGQQQ
RVAIARALAMKPEIMLFDEPTSALDPELVGEVLNVMLSLAKEGMTMVCVTHEIGFAREVA
DQIVFMDGGVVVEKGGPEIIDNPTEPRFKDFLQHVL