Protein Info for BBR_RS13005 in Bifidobacterium breve UCC2003

Annotation: aminopeptidase N

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 869 TIGR02412: aminopeptidase N" amino acids 5 to 865 (861 residues), 914.5 bits, see alignment E=3.5e-279 PF17900: Peptidase_M1_N" amino acids 21 to 203 (183 residues), 51.3 bits, see alignment E=2.5e-17 PF01433: Peptidase_M1" amino acids 247 to 461 (215 residues), 194.6 bits, see alignment E=2.6e-61 PF11838: ERAP1_C" amino acids 545 to 855 (311 residues), 150.4 bits, see alignment E=1.3e-47

Best Hits

KEGG orthology group: K01256, aminopeptidase N [EC: 3.4.11.2] (inferred from 94% identity to blf:BLIF_0438)

Predicted SEED Role

"Membrane alanine aminopeptidase N (EC 3.4.11.2)" (EC 3.4.11.2)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (869 amino acids)

>BBR_RS13005 aminopeptidase N (Bifidobacterium breve UCC2003)
MPGSNLTRVEAEARKAIVEAPIHYHVDLDLTVGPKNFGSKALICFNAKPGSSTFLDLIAD
EVTAIELNGKSLDPATAFQDNRIELTDLKEKNEVTVEALCRYSNTGEGLHRSVDPSDGNI
YLYSQFEVPDARRVYAVFDQPDLKATFDFKVLAPASWIVTSNMPVATIEDDPRETLDGTL
GDKPNESTRLWDFQPTPVMSSYLTAICAGPYAEWHTEYLNEDGRTVPMAQYCRQSLAEAF
SKDVDYLFDITKKGFAFYAKTWGVPYPYAKFDQIYVPEYNAGAMENIGMVTIRDSYVFES
KVTDALAERRVVTVLHELAHMWFGDYVTMKWWNDLWLNESFAEFTSTLATAEATEWHDAW
ATFCSGEKSWALRQDQLPTTHPIVAPINDLNDTYVNFDGITYAKGASVLKQLVFYVGRER
FFEGIHNYLIRHAYSNATLADLLGELEKTSGRDLKAWSAKWLEESGINTIAADIKANANG
TIAELKLTQSAPAEHPVLRPHRLAIGFYNEDAETGKIARTEQFELDVDGETTIVEAAAGK
QRPAFVLINDDDLTYTKIRFDAESQAFAEANLQRFDDALARAVTWLAFWDMTRDGEFPAE
RFVDMTLRLLATETESTTFRYALACMSTTAHHYVAPARREEVLRHVAAELWTLANAAEAG
SDTQFQLATAYLGYGEEGDAAFAVNARGLLDGTVTLDGLDIDNNFTWTIIQSLTSVNEMT
NEDVDAQLAKKDTTENREFAYGARASMATVEAKEWAWDQALHNDELTNSQLEAVARGFSA
TPRADLVEPFAAKYFETVDWVWANKTYHMAEALLNGLYPGYADPATLTKLGDAWLEEHIA
ADNALKRLIVENVASSHRTLKVREYNEAL