Protein Info for BBR_RS12960 in Bifidobacterium breve UCC2003

Annotation: DUF58 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 transmembrane" amino acids 56 to 76 (21 residues), see Phobius details amino acids 82 to 101 (20 residues), see Phobius details PF01882: DUF58" amino acids 238 to 315 (78 residues), 69.6 bits, see alignment E=1.1e-23

Best Hits

KEGG orthology group: None (inferred from 60% identity to blj:BLD_0959)

Predicted SEED Role

"FIG002343: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (429 amino acids)

>BBR_RS12960 DUF58 domain-containing protein (Bifidobacterium breve UCC2003)
MTGPSVTIAHHTRQYGHDNKTEAKHSGGIAHHTRQLGQACRQATARIRHCLTSSVSPLGW
AATGCGTACLCAFPLLGWIELLTFGIASTTMMLCAILLALGNTKFDASIHVSRHRITVDG
TISITVNISNSGTAPTTNTQGGLPIGNDRHRFSIPRLLPKQTKHISMEFHAPARTVLPIG
PLHIRKGDPFGLTRHENDLAERINVYIHPKIVRLPLLHAGIPRDLEGQSSRRIADDDIDF
HGLRKYQPGDDIRNVHWPSSAKADSLMIRQYEATCRTDTSLTLSVDESDYASREEFEMAV
SIHASIGVQCLLQYRPLYVHVGKAHTQPHDAMSFLDATSAIAFQQDFTASLVDGTLQHSA
NASLYVVTVGSKKTLSRITRMARALPQSARCIVLQADIGMTCSIRRCANCTVITIGKLND
LPLMLGVVP