Protein Info for BBR_RS12910 in Bifidobacterium breve UCC2003

Annotation: galactokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 416 TIGR00131: galactokinase" amino acids 18 to 396 (379 residues), 281.8 bits, see alignment E=4.1e-88 PF10509: GalKase_gal_bdg" amino acids 22 to 70 (49 residues), 74.3 bits, see alignment 6.6e-25 PF00288: GHMP_kinases_N" amino acids 130 to 196 (67 residues), 46.9 bits, see alignment E=4.6e-16 PF08544: GHMP_kinases_C" amino acids 314 to 394 (81 residues), 62.8 bits, see alignment E=4.9e-21

Best Hits

KEGG orthology group: K00849, galactokinase [EC: 2.7.1.6] (inferred from 99% identity to blj:BLD_0973)

Predicted SEED Role

"Galactokinase (EC 2.7.1.6)" in subsystem Lactose and Galactose Uptake and Utilization (EC 2.7.1.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (416 amino acids)

>BBR_RS12910 galactokinase (Bifidobacterium breve UCC2003)
MSAVEFIEPLTHEEGVSQATKLFVDTYGAAPEGVWAAPGRVNLIGEHTDYNAGLCLPIAL
PHRTFIALKPREDTKVRVVSGVAPDKVAEADLDGLKARGVDGWSAYPTGVAWALRQAGFD
KVKGFDAAFVSCVPLGSGLSSSAAMTCSTALALDDVYGLGYGDSDAGRVTLINAAIKSEN
EMAGASTGGLDQNASMRCTEGHALLLDCRPELTPLENVSQQEFDLDKYNLELLVVDTQAP
HQLNDGQYAQRRATCEEAAKILGVANLRVTADGISKADDQFQALKETLDALPDETMKKRV
RHVVTEIERVRSFVRAFAQGDIKAAGRLFNASHDSLAADYEVTVPELDIAVDVARKNGAY
GARMTGGGFGGSIIALVDKGRSQEVAQKIADEFEKQGFHAPRALAAYAAPSASREA