Protein Info for BBR_RS12545 in Bifidobacterium breve UCC2003

Annotation: DUF4012 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 586 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF13196: DUF4012" amino acids 203 to 351 (149 residues), 146.1 bits, see alignment E=5.4e-47

Best Hits

KEGG orthology group: None (inferred from 98% identity to blo:BL0250)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (586 amino acids)

>BBR_RS12545 DUF4012 domain-containing protein (Bifidobacterium breve UCC2003)
MVLILALLVVLLGVSGFFGLKLYSEAKQVKAHEEQAMQLLGGVTDLSNLDNLDTVSQQIS
QAKTETSAANEIAHGTLWNIASKAPVYGDDITTVQGMTSVVDSLVSDSVPQFMDVLSTLK
STQLSSGDGQLNLRPILEAQKNIATANQSLQQQVQKYQQLPKAHIGMVKNAYATGNTQLT
KMADKVNQLSGTFQILPDFLGSDQPRTYALMAMTTSEERSSGGLIGSVGVVTTDNGKISI
GDFRSNGEYIPYGAGDPTEDEQRIFRQWGPLNMSFDVRDLAVYPDTSRSAEGMRAIWQRT
PWGSNTQLDGVLMVDPVFLQELTKISGNVTIPDGTVLTGDNTAEFLLNKVYVDYPVSMQD
ALFAQVAEQTVGSMFSNVDLTKLTKVAQLMGSMAEGRHFSMYAFDETAEKTISDAGFTAQ
TPSSEEHPQVGVYVTEQNPSKMGWYIHRTSKVTRSTCGNDGSQTYHVEYKMTNTLENSQI
GALTSYILGPGGQGVEKTLIYAPAGGSISNLKTSGGSVTESRQETMNGKTVYASNATIAP
GESVTYSFDVTTSTKAVSDLTIDQTPMGWIDSGVTTDTAACSINKQ