Protein Info for BBR_RS12330 in Bifidobacterium breve UCC2003

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 737 PF00005: ABC_tran" amino acids 23 to 152 (130 residues), 73.2 bits, see alignment E=1e-23 amino acids 413 to 547 (135 residues), 72.7 bits, see alignment E=1.5e-23 PF16326: ABC_tran_CTD" amino acids 674 to 734 (61 residues), 48 bits, see alignment 3.5e-16

Best Hits

KEGG orthology group: None (inferred from 89% identity to blb:BBMN68_1062)

Predicted SEED Role

"COG0488: ATPase components of ABC transporters with duplicated ATPase domains" in subsystem Folate Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (737 amino acids)

>BBR_RS12330 ABC transporter ATP-binding protein (Bifidobacterium breve UCC2003)
MPTYDIGLEHVSLAFATKTIFTDVTQGVFEGDRIGIVGKNGDGKSTLLHLFRGTQEPDSG
RVTKRGGLTFGMLDQRDPLDDNATIREAALEGRADYEWASDNTSREIVEALLGGMSLDAK
VGSLSGGQRRRADLARLLLKDWDILALDEPTNHLDVVTIHWLAEHLKNRWSKGQGVLLLV
THDRWFLDEVCESMWEVHDGVIEPFEGGYSAYMLQRVERDRQADVRETKRRNLARKELAW
LSRGARARSTKQKFHVKAARELIADVPPMRNTVELKQMATSRLGKQVVDLINVTQIFEHT
QGMAEIDPDVAALADSASRVDVVNAMYAEPQLHGSVEVAVTDMDDPRLVDAGVPEAIEAA
AKAREAEANAPSDIEREVRRQNTGGETIGSDALDEEAATSAARKVTVSGREILDDVTWLI
GPGDRFGIVGANGAGKSTLLKLIDGTLTPTVGHVNIGKTVKFAVLSQRLDELEKLGRYKI
KEVLSRYKPSYIVEGKEVTPGQLMERLGFESAQLMTPIRDLSGGQKRRMQLLLILLDEPN
VLIMDEPGNDLDTDMLAVMEDLLDTWPGTLIVVSHDRYLLERVTDQQFALIGGKVRHLPG
GVQDYLDMVEDLKNGKGLPEDKAGFAGTGGSSAKRGAQGKGSAAESLPQSTSSEGTQDSA
EPKLSGKAFHEASKRVNAIERKLAKLEEQKSDLEAQMASHDPSDYEGLNKLNEQLTAVNG
ESDDLEAEWLELSEQLE