Protein Info for BBR_RS12260 in Bifidobacterium breve UCC2003

Annotation: LemA family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 195 transmembrane" amino acids 6 to 29 (24 residues), see Phobius details PF04011: LemA" amino acids 43 to 194 (152 residues), 197.2 bits, see alignment E=6.5e-63

Best Hits

Swiss-Prot: 40% identical to LEMA_STRGC: Protein LemA (lemA) from Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288)

KEGG orthology group: K03744, LemA protein (inferred from 88% identity to blm:BLLJ_0301)

Predicted SEED Role

"LemA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (195 amino acids)

>BBR_RS12260 LemA family protein (Bifidobacterium breve UCC2003)
MSAGLIITIVVVVVVVVIVALIAWAVGAYNNLVTLKNRVKNGWAQIDVQLKQRADLIPNL
VNTVKGYATHESEVFTQVTAARAGVVAAANDPNATTAQRAAAENQLSRALVNLQATAEAY
PQLQANQNFMDLQAQLKDLENKIAYARQFYNDVVLKLNTAIETVPTNIIAGLFHFEQAQY
FEADDASRQAPQVKL