Protein Info for BBR_RS12215 in Bifidobacterium breve UCC2003

Annotation: VWA domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1242 signal peptide" amino acids 1 to 45 (45 residues), see Phobius details transmembrane" amino acids 1215 to 1236 (22 residues), see Phobius details PF00092: VWA" amino acids 511 to 629 (119 residues), 26 bits, see alignment E=1.5e-09 PF13519: VWA_2" amino acids 512 to 625 (114 residues), 38.2 bits, see alignment E=3e-13 PF05738: Cna_B" amino acids 932 to 1013 (82 residues), 34.2 bits, see alignment 4.4e-12

Best Hits

KEGG orthology group: None (inferred from 97% identity to bll:BLJ_1802)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1242 amino acids)

>BBR_RS12215 VWA domain-containing protein (Bifidobacterium breve UCC2003)
MKRIAEWFAAVGAAASKSGKRLVAVVAAVAMLGGVAGVSATAMADDQSAADTQQPTAQTE
TPANTDSKDAGTDTGSKDDSTKADATKSDDAASADTDAAASELTEQTAPAPTSTLNTQAA
EATNGSCVYAGNVASGLNNVCWLDMTNFTADKDQLQPMSVKLSDSLTMKFNIKYTGGRKL
RSAAVPTWNKAAFGHYGYAGFPEGTKPALYQITGSYNTESTVELTDIKIVNADGSEITGN
YSFMMADAESTNNDESISFTSSNEIEQVAQFPQQGDANYKNYAFGDQTFSADHKTVTGGG
VSPGANPGIYLYKTKSPDTASVTMGVHYGREIQAAIFGVLFSNAETTVTTNNASDTFAGK
VESQTYGSEQTGGVTGSNSATSKVVNMLSDTDTSEQVKFTLSASENTNWNDYNVSFTCDG
DCGEYDATPQIDTATGNRYVTVSVASEKSAHGKWVVTKKVKLDTPKIQKSISKDEVDSAA
TGQKDSYTLSLNVKGNTVSGTTTSGEKAKIDVAFVLDTSGSMNDKVGNSTRLKNMQNAIT
GNGGLSSVLFNSPNKIDAQAHVITFASGLGLDGTSVLSTKADLDNTVNGLTAKGGTHWEK
GLEQVSNISTRPGAAKYVVFLTDGNPGDKGWQKSNVYSCGVLGWQTCDDNDSARSVYNAS
VIAGKQLAKAGWNILNVGVDMPTTVYVNPDADSVSGSNYDLRNHSFSQTAGWVSPLEALT
ARENANKSATVKDQLIKAYPKTTSSELAQVFKDLGQIITTTTTKSYGKVSIVDTLSDYAD
PLFEYDKQSGEITSGVTVVTSDRSNVDAEVASKTYDVATRTVTVTFRDGFTLAKDVTYSV
QFKVKPSDKAYETYASNKQSEKGGYTDTDNTVHQGETGTGTDSENKDGFYSNAEAHLAYS
ECTAVNNVAKDCVSKDNVTYQKPVLQVKTGKIQVTKKWDPTDSEPKDGSKVTVNIYKGDH
ADDGQKVDTLTLAKDGGWTGSLGNLAPGTYFVEETNVDGYTASYSQSQTVTITADDLWKA
EPNMTKFDNVKTYDVTITNTLNRVDLDVNANVKVSKTVQGAAASKDFTFNLTCAKSNAAC
KDGVTWPKDSNGSLTATASKSDLQTIGTPADAKFPDGSTLQLKAPTGTTSAVYEFTVSED
QSGNPAGWKYDTDTVTVKVTVSKKTDGSGYKTNVEYVYADGDSDKTDNPKSADFTNVFVA
VSSLPVTGGRSARDWLIYGGGLGLLALLAGAGYTVWRKRQLV