Protein Info for BBR_RS11505 in Bifidobacterium breve UCC2003

Annotation: TetR/AcrR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 transmembrane" amino acids 146 to 165 (20 residues), see Phobius details PF00440: TetR_N" amino acids 11 to 54 (44 residues), 55.1 bits, see alignment 2.7e-19

Best Hits

KEGG orthology group: None (inferred from 87% identity to blb:BBMN68_1182)

Predicted SEED Role

"Transcriptional regulator, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (276 amino acids)

>BBR_RS11505 TetR/AcrR family transcriptional regulator (Bifidobacterium breve UCC2003)
MTSLQRREQLIEIGRALFAAKGFEAVSVEEIAAHAKVSKPIVYEHFGGKEGLYAVIVDRE
MRALTSVLEAALDDPTVNPRQIVERTALALLTYIEENAEGFQVLVRDSPSTDPSGSFSSL
LGDIAVRVEDILSETFKRQKLSVKGVPYYAQMLVGMTVFTGQYWADRPKVSKEQLAAYIV
DLAWHGLSRLDSKPQLLFEGVKARKEAERRAKRGIDAETPVPDGEASSPLKQTDLDHTLR
EDSGLQNVSSGKQVAQHSAEPEAEVLRFEQETEQND